RT Journal Article
SR Electronic
T1 Cerebellar ataxia as a primary manifestation of neuropsychiatric systemic lupus erythematosus
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e236825
DO 10.1136/bcr-2020-236825
VO 14
IS 2
A1 Marie Charmaine C Sy
A1 Nikolai Gil D Reyes
A1 Geraldine T Zamora
A1 Marc Laurence L Fernandez
YR 2021
UL http://casereports.bmj.com/content/14/2/e236825.abstract
AB Acute cerebellar ataxia is a rare primary manifestation of neuropsychiatric systemic lupus erythematosus (NPSLE). We report a case of a 22-year-old woman who presented with gait instability, behavioural changes and new-onset seizures. The tempo of disease progression was explained by an autoimmune cause, eventually fulfilling the criteria for systemic lupus erythematosus. The patient’s neurological symptoms improved markedly following administration of steroids and immunomodulators. A review of literature on cerebellar ataxia in NPSLE and a summary of all reported cases to date are also presented.