TY - JOUR T1 - Localised laryngotracheal amyloidosis: a differential diagnosis not to forget JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-237954 VL - 14 IS - 2 SP - e237954 AU - Catarina Mira AU - Pedro Montalvão AU - Isabel Fonseca AU - Alexandra Borges Y1 - 2021/02/01 UR - http://casereports.bmj.com/content/14/2/e237954.abstract N2 - We present a case of multifocal laryngotracheal amyloidosis (LTA) in a 43-year-old man with persistent and progressive dysphonia and dyspnoea, and a first inconclusive histology. Although laryngeal amyloidosis accounts for fewer than 1% of all benign laryngeal tumours, it is in fact the most common site of amyloid deposition in the head, neck and respiratory tract. The clinical scenario is non-specific and diagnosis depends on a high degree of suspicion and on histology. Imaging is useful in mapping lesions, which are often more extensive than they appear during laryngoscopy. Despite being a benign entity, the prognosis is variable with a high-rate and long-latency recurrences, requiring long-term follow-up. ER -