RT Journal Article
SR Electronic
T1 Acute kidney injury secondary to severe delayed haemolysis in intravenous artesunate use for severe malaria
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e237501
DO 10.1136/bcr-2020-237501
VO 14
IS 1
A1 Leong, Kai Wen
A1 Singh, Kasha P
A1 Leder, Karin
A1 Tong, Steven Y C
YR 2021
UL http://casereports.bmj.com/content/14/1/e237501.abstract
AB The use of artemisinin derivatives has been recommended by the WHO guidelines in malaria treatment largely due to its rapid parasite clearance and safety profile. This case report details the development of delayed haemolysis and subsequent severe acute kidney injury (AKI) 13 days after commencing intravenous artesunate treatment for malaria in an Australian returned traveller. Delayed haemolysis may be an under-recognised complication following artesunate use and if severe, can be complicated by AKI. Therefore, close patient follow-up following treatment is required to ensure prompt recognition of this phenomenon.