PT - JOURNAL ARTICLE AU - Lawrence Langley AU - Claudia Zeicu AU - Louise Whitton AU - Mathilde Pauls TI - Acute disseminated encephalomyelitis (ADEM) associated with COVID-19 AID - 10.1136/bcr-2020-239597 DP - 2020 Dec 01 TA - BMJ Case Reports PG - e239597 VI - 13 IP - 12 4099 - http://casereports.bmj.com/content/13/12/e239597.short 4100 - http://casereports.bmj.com/content/13/12/e239597.full SO - BMJ Case Reports2020 Dec 01; 13 AB - A 53-year-old man admitted to the critical care secondary to respiratory failure due to COVID-19 developed agitation and global hypotonia. Brain MRI revealed bilateral hyperintense lesions throughout the brain and cerebrospinal fluid identified oligoclonal bands. Intravenous high-dose glucocorticoids were administered followed by an oral tapering dose and the patient clinically improved. Acute disseminated encephalomyelitis should be considered in patients with COVID-19 who present with altered mentation and polyfocal neurological deficits.