PT  - JOURNAL ARTICLE
AU  - Jack Italiano
AU  - Rachel Bush
AU  - Ratna Acharya
AU  - Kiran Upadhyay
TI  - Persistent viral shedding despite seroconversion in a kidney transplant recipient with severe extrapulmonary COVID-19
AID  - 10.1136/bcr-2020-239612
DP  - 2020 Nov 01
TA  - BMJ Case Reports
PG  - e239612
VI  - 13
IP  - 11
4099  - http://casereports.bmj.com/content/13/11/e239612.short
4100  - http://casereports.bmj.com/content/13/11/e239612.full
SO  - BMJ Case Reports2020 Nov 01; 13
AB  - Renal transplant (RT) recipients are at increased risk for infectious complications. The clinical course of COVID-19 has been described in several RT recipients with varying clinical outcomes. Most present with pulmonary manifestations, however extrapulmonary presentations are not uncommon. Also, the timing and efficacy of seroconversion in transplant recipients is not well known. This report describes the duration of viral shedding and timing of seroconversion in a young adult RT recipient with COVID-19 who presented with severe diarrhoea and acute kidney injury requiring dialysis. She developed anti‐SARS‐CoV‐2 IgG antibody after 5 weeks despite persistently shedding the virus in the nasopharynx until 6 weeks after symptom onset. Further studies are needed to determine if immunosuppressed patients have prolonged viral shedding and are still contagious despite seroconversion.