RT Journal Article
SR Electronic
T1 Severe hyperthermia due to oral baclofen withdrawal
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e234710
DO 10.1136/bcr-2020-234710
VO 13
IS 9
A1 Vishesh Paul
A1 Kari Righter
A1 Elise Kim
A1 Weston Nadherny
YR 2020
UL http://casereports.bmj.com/content/13/9/e234710.abstract
AB We report a case of a 53-year-old woman who presented initially with sepsis and later in her stay developed a severe and rapidly progressing hyperthermia after a decrease in oral baclofen dosage. Her fever peaked at 42.5○C (108.5○F), creating a broad differential diagnosis and complicating her initial sepsis diagnosis. When the oral baclofen dose was increased, the fevers resolved which confirmed the clinical diagnosis of baclofen withdrawal. Dose reductions of oral baclofen should be made gradually and with caution, and patients should be monitored for fevers as a possible symptom of baclofen withdrawal.