TY - JOUR T1 - Angioedema, ACE inhibitor and COVID-19 JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-237888 VL - 13 IS - 9 SP - e237888 AU - Ekjot Grewal AU - Bayu Sutarjono AU - Ibbad Mohammed Y1 - 2020/09/01 UR - http://casereports.bmj.com/content/13/9/e237888.abstract N2 - SARS-CoV-2, the virus responsible for COVID-19, binds to the ACE2 receptors. ACE2 is thought to counterbalance ACE in the renin-angiotensin system. While presently it is advised that patients should continue to use ACE inhibitors or angiotensin receptor blockers, questions still remain as to whether adverse effects are potentiated by the virus. Here, we report a case of a 57-year-old man, unknowingly with COVID-19, who presented to the emergency department with tongue swelling, shortness of breath and difficulty in speaking following 4 months taking benazepril, an ACE inhibitor. Finally, we also describe possible pathways that exist for SARS-CoV-2 to interact with the mechanism behind angioedema. ER -