TY - JOUR T1 - Elimination of <em>Staphylococcus aureus</em> from the bloodstream using a novel biomimetic sorbent haemoperfusion device JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-235262 VL - 13 IS - 8 SP - e235262 AU - Malin-Theres Seffer AU - Gabriele Eden AU - Susanne Engelmann AU - Jan T Kielstein Y1 - 2020/08/01 UR - http://casereports.bmj.com/content/13/8/e235262.abstract N2 - Removal of bacteria from the blood by means of extracorporeal techniques has been attempted for decades. In late 2019, the European Union licensed the first ever haemoperfusion device for removal of bacteria from the blood. The active ingredient of Seraph 100 Microbind Affinity Blood Filter is ultrahigh molecular weight polyethylene beads with endpoint-attached heparin. Bacteria have been shown to bind to heparin as they would usually do to the heparan sulfate on the cell surface, thereby being removed from the blood stream. We describe the first case of a female chronic haemodialysis patient in which this device was clinically used for a Staphylococcus aureus infection that persisted for 4 days despite antibiotic therapy. After a single treatment, the bacterial load decreased and the blood cultures at the end of a 4 hour haemoperfusion exhibited no bacterial growth. ER -