RT Journal Article
SR Electronic
T1 Multimodality therapy of endometrial glassy cell carcinoma: a rare type of cancer
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e235164
DO 10.1136/bcr-2020-235164
VO 13
IS 6
A1 Vera Kazakova
A1 Yenny Alejandra Moreno Vanegas
A1 Arun Kadamkulam Syriac
A1 Olga Kozyreva
YR 2020
UL http://casereports.bmj.com/content/13/6/e235164.abstract
AB Glassy cell carcinoma (GCC) is a rare histologically aggressive cancer subtype of the cervix that is associated with poor prognosis. Only 16 cases of endometrial GCC (EGCC) have been described in the literature to date. The data on prognostic factors and management of EGCC are limited and no optimal treatment protocol has been established. We describe a case of a 67-year-old woman who presented with postmenopausal bleeding and was diagnosed with stage IA EGCC. The patient’s risk factors included histology, age and lower uterine segment involvement. The patient was successfully treated with total hysterectomy and bilateral salpingo-oophorectomy with pelvic node dissection followed by adjuvant sandwich chemotherapy and radiotherapy. The patient has no evidence of disease recurrence for 18 months. This is the first case of EGCC management with adjuvant multimodality therapy.