RT Journal Article
SR Electronic
T1 Sclerosing angiomatoid nodular transformation of the spleen: unusual case presentation in an intravenous drug user
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e235648
DO 10.1136/bcr-2020-235648
VO 13
IS 6
A1 Carlos Sánchez Belmar
A1 Alexandra White
A1 Mudassar Majeed
A1 Henry Paul Redmond
YR 2020
UL http://casereports.bmj.com/content/13/6/e235648.abstract
AB An unusual presentation of sclerosing angiomatoid nodular transformation in a 42-year-old man who was admitted with jaundice, deranged liver function tests and subsequently diagnosed with acute hepatitis C infection in the context of recent intravenous drug use. During his admission, he had an ultrasound of the abdomen followed by a CT thorax, abdomen and pelvis which showed splenomegaly and a large splenic lower pole mass that was hypoechoic and concerning for lymphoma. A bone marrow biopsy showed no evidence of lymphoma and an ultrasound-guided biopsy of the splenic mass suggested unusual features with vascular proliferation, either neoplastic or reactive, with no evidence of lymphoma or high-grade sarcoma. Given the concern for malignancy, an open splenectomy was required to determine the nature of the lesion with histologic findings consistent with a non-neoplastic benign vascular lesion favouring sclerosing angiomatoid nodular transformation.