PT  - JOURNAL ARTICLE
AU  - Carlos Sánchez Belmar
AU  - Alexandra White
AU  - Mudassar Majeed
AU  - Henry Paul Redmond
TI  - Sclerosing angiomatoid nodular transformation of the spleen: unusual case presentation in an intravenous drug user
AID  - 10.1136/bcr-2020-235648
DP  - 2020 Jun 01
TA  - BMJ Case Reports
PG  - e235648
VI  - 13
IP  - 6
4099  - http://casereports.bmj.com/content/13/6/e235648.short
4100  - http://casereports.bmj.com/content/13/6/e235648.full
SO  - BMJ Case Reports2020 Jun 01; 13
AB  - An unusual presentation of sclerosing angiomatoid nodular transformation in a 42-year-old man who was admitted with jaundice, deranged liver function tests and subsequently diagnosed with acute hepatitis C infection in the context of recent intravenous drug use. During his admission, he had an ultrasound of the abdomen followed by a CT thorax, abdomen and pelvis which showed splenomegaly and a large splenic lower pole mass that was hypoechoic and concerning for lymphoma. A bone marrow biopsy showed no evidence of lymphoma and an ultrasound-guided biopsy of the splenic mass suggested unusual features with vascular proliferation, either neoplastic or reactive, with no evidence of lymphoma or high-grade sarcoma. Given the concern for malignancy, an open splenectomy was required to determine the nature of the lesion with histologic findings consistent with a non-neoplastic benign vascular lesion favouring sclerosing angiomatoid nodular transformation.