RT Journal Article SR Electronic T1 Extra-skeletal Ewing’s sarcoma of the frontal sinus: a rare disorder in pediatric age JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e232460 DO 10.1136/bcr-2019-232460 VO 13 IS 5 A1 Costa, Isabel Esteves A1 Sousa Menezes, Ana A1 Lima, Antonio Fontes A1 Rodrigues, Berta YR 2020 UL http://casereports.bmj.com/content/13/5/e232460.abstract AB Paediatric sinonasal tumours comprise numerous aetiologies. Ewing’s sarcoma (ES) consists of a malignancy of neuroectodermal origin. This type of sarcoma affects mainly children and adolescents and can assume the skeletal or extra-skeletal form. Primary ES of head and neck is extremely rare, accounting for only 4%–9% of all cases. So far, as much as we know, only a few cases of sinonasal ES have been reported in literature. The authors present a case of a previous healthy 12-year-old girl who presented with a rapidly growing and expansive frontal mass and unilateral nasal obstruction. Immunohistochemical, molecular and cytogenetic analysis of the lesion showed diffuse expression of CD56 and CD99 on tumour cells and a translocation involving chromosome 22q12, confirming ES diagnosis.