RT Journal Article SR Electronic T1 Ureaplasma urealyticum infection presenting as pyelonephritis and perinephric abscess in an immunocompromised patient JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e234538 DO 10.1136/bcr-2020-234538 VO 13 IS 5 A1 Alexander Ngoo A1 Jared Eisemann A1 Admire Matsika A1 David Winkle YR 2020 UL http://casereports.bmj.com/content/13/5/e234538.abstract AB We report a case of an immunosuppressed 67-year-old woman who presented with fever of unknown origin. Further investigation revealed multiple left renal and perinephric abscesses. These were managed with percutaneous drainage and broad-spectrum antibiotics; however, no clinical improvement resulted. No organism was identifiable on standard microscopy and culture of all drain, blood and urine samples taken. Left nephrectomy with right urinary diversion was performed for sepsis management and to protect the patient’s right kidney. Eventually, Ureaplasma species’ RNA was detected in the patient’s drain fluid using PCR and 16S ribosomal RNA gene sequencing. The patient was treated successfully with targeted antibiotic therapy and underwent extensive rehabilitation following this. Histopathology of the nephrectomy specimen suggested xanthogranulomatous pyelonephritis.