PT  - JOURNAL ARTICLE
AU  - Yi Lin Lee
AU  - Siying Pang
AU  - Caroline Ong
TI  - Non-cirrhotic hyperammonaemia: are we missing the diagnosis?
AID  - 10.1136/bcr-2019-233218
DP  - 2020 Mar 01
TA  - BMJ Case Reports
PG  - e233218
VI  - 13
IP  - 3
4099  - http://casereports.bmj.com/content/13/3/e233218.short
4100  - http://casereports.bmj.com/content/13/3/e233218.full
SO  - BMJ Case Reports2020 Mar 01; 13
AB  - Hepatic encephalopathy secondary to hyperammonaemia is a known complication of chronic liver disease. In contrast, non-cirrhotic hyperammonaemia is a lesser-known entity that should be considered in a patient with acute encephalopathy as part of the diagnostic workup as prompt identification can help to avoid complications such as seizures and cerebral oedema. We present a case of a middle-aged woman who presented electively for a total pancreatectomy–duodenectomy with splenectomy, hepatico-jejunostomy, gastro-jejunostomy and developed encephalopathy on postoperative day 10 due to non-cirrhotic hyperammonaemia.