RT Journal Article
SR Electronic
T1 Refractory recurrent ocular graft versus host disease
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e232579
DO 10.1136/bcr-2019-232579
VO 12
IS 12
A1 Emily Greenan
A1 Elisabeth Vandenberghe
A1 Conor C Murphy
YR 2019
UL http://casereports.bmj.com/content/12/12/e232579.abstract
AB Ocular graft-versus-host disease (GVHD) is one of the most frequent and long-term complications affecting patients after haematopoietic stem cell transplantation. It is associated with significant morbidity and a marked reduction in quality of life. Although common, currently there are no widely accepted guidelines available for its management, and no suggested regime of treatment that is completely satisfactory. So far, prophylactic treatment strategies for ocular GVHD have yet to be developed and treatment is normally initiated based on symptoms often after permanent ocular tissue changes and surface damage has occurred. Here we describe a case of recurrent ocular GVHD and its associated complications that was highly refractory to treatment.