TY - JOUR T1 - Pulmonary alveolar proteinosis (PAP) in idiopathic hypoparathyroidism JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2019-231053 VL - 12 IS - 11 SP - e231053 AU - Soma Saha AU - Karan Madan AU - Deepali Jain AU - Ravinder Goswami Y1 - 2019/11/01 UR - http://casereports.bmj.com/content/12/11/e231053.abstract N2 - Idiopathic hypoparathyroidism (IH) and autoimmune pulmonary alveolar proteinosis (PAP) are rare disorders. A patient with IH and optimal calcaemic control on calcium and alfacalcidol was detected to have PAP after 8 years of follow-up. Patient had no respiratory complaints. Routine abdominal imaging for renal calcification showed patchy ground glass opacities in the lower lung fields leading to incidental diagnosis of PAP. Pulmonary function tests showed impaired diffusion capacity of the lung. Anti-granulocyte macrophage-colony stimulating factor autoantibodies were positive. Patient regularly attended the pulmonary clinic and showed progressive improvement in diffusion capacity of the lung during 2 years of follow-up. The calcaemic control in IH remained stable despite its presence with PAP. The autoimmune PAP in the presented case suggests a possible autoimmune basis of IH. ER -