RT Journal Article
SR Electronic
T1 New-onset asthma in a bilateral lung transplant patient
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e231654
DO 10.1136/bcr-2019-231654
VO 12
IS 11
A1 Daniel Benjamin Fyenbo
A1 Kristine Bruun Degn
A1 Johannes Martin Schmid
A1 Elisabeth Bendstrup
YR 2019
UL http://casereports.bmj.com/content/12/11/e231654.abstract
AB We present a case of new-onset asthma in a 35-year-old man who had undergone bilateral lung transplantation 11 years before due to idiopathic bronchiectasis and pulmonary hypertension. He presented with recurrent episodes of breathlessness, wheezing and coughing. Spirometry demonstrated severe airway obstruction. After treatment with systemic and inhaled corticosteroids and long-acting bronchodilators as well as short-acting beta-agonists as needed, his symptoms resolved and his spirometry normalised. A bronchial mannitol challenge test showed significant airway hyperresponsiveness and is thus consistent for a diagnosis of asthma. To our best knowledge, this is the first case of late new-onset asthma in a lung transplant recipient.