PT  - JOURNAL ARTICLE
AU  - Kosar Hussain
AU  - Anil Xavier
TI  - Rosuvastatin-related rhabdomyolysis causing severe proximal paraparesis and acute kidney injury
AID  - 10.1136/bcr-2019-229244
DP  - 2019 Oct 01
TA  - BMJ Case Reports
PG  - e229244
VI  - 12
IP  - 10
4099  - http://casereports.bmj.com/content/12/10/e229244.short
4100  - http://casereports.bmj.com/content/12/10/e229244.full
SO  - BMJ Case Reports2019 Oct 01; 12
AB  - We describe the case of a 76-year-old man who presented with bilateral lower limb weakness associated with decreased urine output. His initial blood results showed acute kidney injury (AKI) stage 3 with substantially raised serum creatine kinase concentration of 37 950 IU/L (normal range <171 U/L). He had been on high-dose rosuvastatin for 4 years with a recent brand change occurring 1 week prior to onset of symptoms. There was no history of pre-existing neuromuscular disease. Statin-related rhabdomyolysis was suspected and rosuvastatin was withheld. His muscle strength gradually improved. He required haemodialysis for 10 weeks. He was discharged home after a complicated course of hospitalisation. His renal function improved and he became dialysis-independent; however, he was left with residual chronic kidney disease.