TY - JOUR T1 - Clozapine-induced stercoral colitis: a surgical perspective JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2018-227718 VL - 12 IS - 8 SP - e227718 AU - Jayan George AU - Richard Hotham AU - William Melton AU - Keith Chapple Y1 - 2019/08/01 UR - http://casereports.bmj.com/content/12/8/e227718.abstract N2 - We describe a case of a 46-year-old man with schizophrenia treated with clozapine who presented as an emergency with abdominal pain on the background of a 1 month history of constipation. The initial presenting symptoms were vague and a diagnosis was difficult to establish. Initial CT of the abdomen and pelvis demonstrated only minor abnormalities. He continued to deteriorate until a further CT scan revealed worsening stercoral colitis. He subsequently underwent an emergency total colectomy and ileostomy formation and had a complicated prolonged postoperative recovery. This case highlights the risks that clozapine can have on slowing bowel transit and the dangerous consequences that can occur if not identified early. ER -