PT - JOURNAL ARTICLE AU - Jayan George AU - Richard Hotham AU - William Melton AU - Keith Chapple TI - Clozapine-induced stercoral colitis: a surgical perspective AID - 10.1136/bcr-2018-227718 DP - 2019 Aug 01 TA - BMJ Case Reports PG - e227718 VI - 12 IP - 8 4099 - http://casereports.bmj.com/content/12/8/e227718.short 4100 - http://casereports.bmj.com/content/12/8/e227718.full SO - BMJ Case Reports2019 Aug 01; 12 AB - We describe a case of a 46-year-old man with schizophrenia treated with clozapine who presented as an emergency with abdominal pain on the background of a 1 month history of constipation. The initial presenting symptoms were vague and a diagnosis was difficult to establish. Initial CT of the abdomen and pelvis demonstrated only minor abnormalities. He continued to deteriorate until a further CT scan revealed worsening stercoral colitis. He subsequently underwent an emergency total colectomy and ileostomy formation and had a complicated prolonged postoperative recovery. This case highlights the risks that clozapine can have on slowing bowel transit and the dangerous consequences that can occur if not identified early.