RT Journal Article
SR Electronic
T1 Subcutaneous mass concerning for sarcoma: a peculiar presentation of diffuse large B-cell lymphoma
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e229327
DO 10.1136/bcr-2019-229327
VO 12
IS 7
A1 John Mayo
A1 Kenneth Bogenberger
A1 Thomas Raj
A1 Jeffrey Reha
YR 2019
UL http://casereports.bmj.com/content/12/7/e229327.abstract
AB Diffuse large B-cell lymphoma (DLBCL) can present in a number of different ways, including as a primary cutaneous lesion or at various other extranodal sites. However, it is rare for a DLBCL to present as a clinically subcutaneous mass without visible skin changes or nodal involvement. A 36-year-old man presented with a 4×4×1 cm subcutaneous mass to his shoulder with normal overlying skin which had been enlarging over 6 months. Physical exam and imaging together made a strong case for sarcoma, and the patient underwent a radical resection. The final pathological diagnosis returned as a diffuse B-cell lymphoma (germinal centre type). The patient subsequently healed and tolerated chemotherapy well. DLBCL can masquerade as a soft tissue mass at initial presentation. If the diagnosis is not clear, a biopsy should be pursued.