TY - JOUR T1 - Metastatic prostate cancer presenting as tumour-induced osteomalacia JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2019-229434 VL - 12 IS - 7 SP - e229434 AU - Awo Akosua K Layman AU - Shivam Joshi AU - Sanjeev Shah Y1 - 2019/07/01 UR - http://casereports.bmj.com/content/12/7/e229434.abstract N2 - Tumour-induced osteomalacia (TIO), or oncogenic osteomalacia, is a paraneoplastic syndrome marked by hypophosphataemia, renal phosphate wasting, bone pain, weakness, and fractures. The syndrome has been reported with both benign and malignant tumours including parotid gland basal cell tumours, thyroid carcinomas, colon adenocarcinomas, and prostate cancer. Often, the syndrome is marked by an insidious course during which patients present with generalised bony pain and weakness, which do not resolve until the underlying tumour is identified and treated. We present a case of a patient with Parkinson’s disease whose subacute weakness, lower extremity paresis, and renal phosphate wasting led to the synchronous diagnosis of metastatic prostate adenocarcinoma and TIO. ER -