TY - JOUR T1 - Acute splenic infarction presenting as an unusual manifestation of essential thrombocythaemia with normal platelet count JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2019-229387 VL - 12 IS - 7 SP - e229387 AU - Katsuyuki Yoshida AU - Ibuki Kurihara AU - Takahiko Fukuchi AU - Hitoshi Sugawara Y1 - 2019/07/01 UR - http://casereports.bmj.com/content/12/7/e229387.abstract N2 - Essential thrombocythaemia (ET) is characterised by elevated platelet count by a clonal stem cell disorder of megakaryocytes. Although thrombosis is a common complication of ET, splenic infarction (SI) is extremely rare. Here, we present the case of a 31-year-old Japanese man who presented with sudden-onset severe pain at the left hypochondrium on the day before admission. Enhanced abdominal CT revealed SI. The laboratory test results revealed a normal platelet count (439×109/L). Subsequently, the patient was diagnosed with ET because the platelet count gradually increased to 50.0×104/μL, and JAK2 V617F mutation was identified. Accordingly, low-dose aspirin was initiated, and no thrombotic episode occurred. Nevertheless, 6 months postdischarge, the platelet count gradually increased to >650 × 109/L, and anagrelide was initiated. This case demonstrates an unusual complication of acute SI due to ET under the rare situation of the normal platelet count. ER -