RT Journal Article
SR Electronic
T1 Direct oral anticoagulant and AKI: apixaban-induced acute interstitial nephritis
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e230371
DO 10.1136/bcr-2019-230371
VO 12
IS 6
A1 Christina DiMaria
A1 Wael Hanna
A1 Julie Murone
A1 James Reichart
YR 2019
UL http://casereports.bmj.com/content/12/6/e230371.abstract
AB Direct oral anticoagulants (DOACs)—dabigatran, rivaroxaban, apixaban and edoxaban—are changing the landscape of clinical practice for patients requiring short and long-term anticoagulation. We report a patient with no history of kidney disease developing acute interstitial nephritis (AIN) after starting a DOAC, apixaban. To date, this is the first biopsy proven case of apixaban-induced AIN.