RT Journal Article
SR Electronic
T1 Takotsubo twins
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e227885
DO 10.1136/bcr-2018-227885
VO 12
IS 4
A1 Ekenbäck, Christina
A1 Tornvall, Per
A1 Spaak, Jonas
YR 2019
UL http://casereports.bmj.com/content/12/4/e227885.abstract
AB Takotsubo syndrome is an intriguing condition of often stress induced reversible cardiac dysfunction mimicking myocardial infarction, but without explanatory coronary obstructions. The pathogenesis of the syndrome is not yet fully understood, though altered sympathetic regulation or response to cardiac sympathetic stimuli is likely to be involved. We present a unique and clinically detailed report of identical twin sisters, who both developed Takotsubo syndrome in association to mental stress shortly after menopause, also covering a potential relapse of disease in one of the twins, supporting the theory of a genetic contribution to the development of the syndrome proposed by previous case reports and small genetic studies.