TY - JOUR T1 - Takotsubo twins JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2018-227885 VL - 12 IS - 4 SP - e227885 AU - Christina Ekenbäck AU - Per Tornvall AU - Jonas Spaak Y1 - 2019/04/01 UR - http://casereports.bmj.com/content/12/4/e227885.abstract N2 - Takotsubo syndrome is an intriguing condition of often stress induced reversible cardiac dysfunction mimicking myocardial infarction, but without explanatory coronary obstructions. The pathogenesis of the syndrome is not yet fully understood, though altered sympathetic regulation or response to cardiac sympathetic stimuli is likely to be involved. We present a unique and clinically detailed report of identical twin sisters, who both developed Takotsubo syndrome in association to mental stress shortly after menopause, also covering a potential relapse of disease in one of the twins, supporting the theory of a genetic contribution to the development of the syndrome proposed by previous case reports and small genetic studies. ER -