PT  - JOURNAL ARTICLE
AU  - Dracham, Chinna Babu
AU  - Gupta, Shipra
AU  - Das, Chandan Krushna
AU  - Elangovan, Arun
TI  - Platinum sensitive carcinoma of ovary relapsed as pericardial effusion with cardiac tamponade
AID  - 10.1136/bcr-2018-228268
DP  - 2019 Mar 01
TA  - BMJ Case Reports
PG  - e228268
VI  - 12
IP  - 3
4099  - http://casereports.bmj.com/content/12/3/e228268.short
4100  - http://casereports.bmj.com/content/12/3/e228268.full
SO  - BMJ Case Reports2019 Mar 01; 12
AB  - Epithelial ovarian cancers typically spread by intraperitoneal exfoliation and retroperitoneal lymph nodal involvement along the ovarian vascular supply. Pericardial involvement in ovarian malignancies is very rare with only few cases reported in the literature. Malignancy is the most common cause for pericardial effusion in the western world. In this case report, we present a 58-year-old woman treated for high-grade serous carcinoma of the ovary in 2010, relapsed with pericardial effusion and cardiac tamponade in 2017. Imaging studies revealed gross pericardial effusion. Two-dimensional echocardiogram showed massive pericardial effusion, with cardiac tamponade, New York Heart Association—IV. Pericardiocentesis and pigtail drain was placed under echo guidance. Immunocytochemistry has confirmed the tumour cells to be of the ovarian origin. The patient underwent surgical pericardial window via thoracotomy, followed by paclitaxel and carboplatin-based chemotherapy and olaparib maintenance.