RT Journal Article
SR Electronic
T1 Donepezil: an unusual therapy for acute diphenhydramine overdose
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e226836
DO 10.1136/bcr-2018-226836
VO 12
IS 3
A1 Jamia Ahmad
A1 Md Jahidul Hasan
A1 Ahmad Mursel Anam
A1 Dipesh Kumar Barua
YR 2019
UL http://casereports.bmj.com/content/12/3/e226836.abstract
AB An elderly man presented with the history of diphenhydramine hydrochloride overdose as a suicidal attempt. At presentation, he was in an acute confusional state with several anticholinergic features and had to be managed in intensive care unit. As an antidote for diphenhydramine hydrochloride, donepezil was used instead of physostigmine due to the unavailability of physostigmine in Bangladesh. The patient improved within the next 24 hours; his level of consciousness improved and the anticholinergic features regressed.