RT Journal Article
SR Electronic
T1 Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e227233
DO 10.1136/bcr-2018-227233
VO 12
IS 3
A1 Jessica Feng
A1 Avery LaChance
A1 David A Sinclair
A1 Maryam M Asgari
YR 2019
UL http://casereports.bmj.com/content/12/3/e227233.abstract
AB A man in his early 60s with myotonic dystrophy type 1 (DM1) and an extensive history of non-melanoma skin cancer presented with multiple pearly, erythematous papules on his face, head, trunk and extremities, clinically consistent with basal cell carcinoma (BCC). Due to the numerous BCC and history of multiple and early-onset BCC, examination was concerning for a hereditary BCC syndrome. Subsequent histopathology confirmed BCC. Genetic testing was negative for basal cell nevus syndrome and clinical findings were inconsistent with other known hereditary BCC syndromes. There have been reports of an association between DM1 and BCC, however, it is not well known among clinicians. We hope to raise awareness among clinicians about this association.