%0 Journal Article %A Dileep Kumar %A Mary King %A Belinda Jim %A Anjali Acharya %T Recurrent case of pregnancy-induced atypical haemolytic uremic syndrome (P-aHUS) %D 2019 %R 10.1136/bcr-2018-226571 %J BMJ Case Reports %P bcr-2018-226571 %V 12 %N 1 %X Pregnancy-induced atypical haemolytic uremic syndrome (P-aHUS) is a rare condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia and renal failure. It accounts for approximately 7% of total HUS cases. Here, we present a case of recurrent P-aHUS in a 25-year-old Hispanic woman. Pregnancy was the clear trigger in both instances, and the disease manifested in first week of the postpartum period. Because of her significant obstetric history, a multidisciplinary approach was adopted to monitor her second pregnancy antepartum and post partum. As the patient developed recurrence of P-aHUS 4 days after her delivery, she was immediately administered eculizumab within few hours of disease manifestation. The patient normalised her haematological parameters within 1 week but sustained dialysis-requiring renal failure for a total of 6 weeks. This case highlights the advances as well as the ongoing uncertainties, especially with respect to the use of eculizumab, in this rare but morbid disease. %U https://casereports.bmj.com/content/bmjcr/12/1/bcr-2018-226571.full.pdf