PT  - JOURNAL ARTICLE
AU  - Jenan Ghaith
AU  - Ismail A Raslan
AU  - Andrew Szilagyi
AU  - Mona Alameldin
TI  - Case of olmesartan-associated enteropathy and transient positive antitissue transglutaminase serology
AID  - 10.1136/bcr-2018-225518
DP  - 2018 Nov 01
TA  - BMJ Case Reports
PG  - e225518
VI  - 11
IP  - 1
4099  - http://casereports.bmj.com/content/11/1/e225518.short
4100  - http://casereports.bmj.com/content/11/1/e225518.full
SO  - BMJ Case Reports2018 Nov 01; 11
AB  - Olmesartan-associated enteropathy (OAE) is increasingly being recognised as a major differential diagnosis in patients with villous atrophy and negative coeliac disease (CD) serology. OAE and positive coeliac markers have rarely been reported. We report a case of diarrhoea and small bowel villous blunting associated with a transient elevation of antitissue transglutaminase antibody (ATTG). On discontinuation of olmesartan, symptoms improved, repeat biopsies were normal and levels of ATTG also returned normal. We discuss a possible explanation for the transient elevation in ATTG and the significance of considering OAE/CD overlap.