RT Journal Article
SR Electronic
T1 Influenza-induced rhabdomyolysis
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e226610
DO 10.1136/bcr-2018-226610
VO 11
IS 1
A1 Martin Runnstrom
A1 Alex M Ebied
A1 Adonice Paul Khoury
A1 Raju Reddy
YR 2018
UL http://casereports.bmj.com/content/11/1/e226610.abstract
AB Rhabdomyolysis is characterised by muscle breakdown with release of damaging proteins that can have devastating consequences. Acute influenza infection is being increasingly recognised as an underlying aetiology. We report an unusual case of severe rhabdomyolysis with acute renal failure due to influenza A infection that improved with high-dose oseltamivir and intravenous fluids. In our case, we also noticed a temporal relation between fever spikes and subsequent increase in serum creatine kinase. The precise mechanism between the rise in temperature and creatine kinase is unclear but it could be due to direct viral invasion of myocytes or due to release of new viral progeny following replication in the myocyte.