PT  - JOURNAL ARTICLE
AU  - Runnstrom, Martin
AU  - Ebied, Alex M
AU  - Khoury, Adonice Paul
AU  - Reddy, Raju
TI  - Influenza-induced rhabdomyolysis
AID  - 10.1136/bcr-2018-226610
DP  - 2018 Nov 01
TA  - BMJ Case Reports
PG  - e226610
VI  - 11
IP  - 1
4099  - http://casereports.bmj.com/content/11/1/e226610.short
4100  - http://casereports.bmj.com/content/11/1/e226610.full
SO  - BMJ Case Reports2018 Nov 01; 11
AB  - Rhabdomyolysis is characterised by muscle breakdown with release of damaging proteins that can have devastating consequences. Acute influenza infection is being increasingly recognised as an underlying aetiology. We report an unusual case of severe rhabdomyolysis with acute renal failure due to influenza A infection that improved with high-dose oseltamivir and intravenous fluids. In our case, we also noticed a temporal relation between fever spikes and subsequent increase in serum creatine kinase. The precise mechanism between the rise in temperature and creatine kinase is unclear but it could be due to direct viral invasion of myocytes or due to release of new viral progeny following replication in the myocyte.