TY - JOUR T1 - Acute retinal necrosis (ARN) following chickenpox in a patient of Vogt-Koyanagi-Harada (VKH) syndrome using immunosuppressants JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2018-227290 VL - 11 IS - 1 SP - e227290 AU - Rajan Gupta AU - Mudit Tyagi AU - Divya Balakrishnan AU - Padmaja Kumari Rani Y1 - 2018/11/01 UR - http://casereports.bmj.com/content/11/1/e227290.abstract N2 - A 36-year-old woman presented with diminution of vision and floaters in both the eyes. Both eyes had disc oedema, multiple pockets of neurosensory detachments along with vitritis. Fluorescein angiography and optical coherence tomography showed characteristic features of Vogt-Koyanagi-Harada (VKH) syndrome (figure 1). She was started on corticosteroid pulse therapy and immunosuppressants following which her VKH lesions resolved. However, she developed chickenpox after 2 weeks and after 1 month she developed discrete yellowish white retinitis patches in the periphery of the right eye which were consistent with a diagnosis of acute retinal necrosis. She was started on oral antivirals for the same and immunosuppressants were withheld in view of immunocompromised state potentially acting as a trigger for reactivation of latent virus. Retinitis patches started to resolve and showed a favourable response to the treatment. ER -