PT  - JOURNAL ARTICLE
AU  - Vincenzo Di Stefano
AU  - Cristina Valdesi
AU  - Marinella Zilli
AU  - Marta Peri
TI  - Pancoast’s syndrome caused by lymph node metastasis from breast cancer
AID  - 10.1136/bcr-2018-226793
DP  - 2018 Nov 01
TA  - BMJ Case Reports
PG  - e226793
VI  - 11
IP  - 1
4099  - http://casereports.bmj.com/content/11/1/e226793.short
4100  - http://casereports.bmj.com/content/11/1/e226793.full
SO  - BMJ Case Reports2018 Nov 01; 11
AB  - Pancoast’s syndrome may be the result of neoplastic, inflammatory or infectious disease. We report an unusual case of Pancoast’s syndrome in a patient with metastatic breast cancer. A 54-year-old woman, affected by metastatic breast cancer, presented for severe shoulder pain, paraesthesia and numbness in the right arm. Despite further multiple lines of systemic chemotherapy, she developed a progressive enlargement of retropectoral, supraclavicular and infraclavicular lymph node metastases, which involved brachial plexus, apex of lung and anterior mediastinum. Physical examination revealed severe weakness of proximal muscles of the right arm. Neuropathic pain was managed with pharmacological treatment. Lastly, the patient has been treated with intrathecal analgesia with morphine and ziconotide with a good control of pain. The patient died after 3 months.