TY - JOUR T1 - Use of mineral trioxide aggregate for retreatment of a tooth with large periapical lesion, wide-open apices and vertical root fracture JF - BMJ Case Reports DO - 10.1136/bcr-2018-227627 VL - 2018 SP - bcr-2018-227627 AU - Pragya Pandey AU - Tanya Nandkeoliar AU - Rhythm Bains AU - Diksha Singh Y1 - 2018/11/05 UR - http://casereports.bmj.com/content/2018/bcr-2018-227627.abstract N2 - Chronic periapical lesions in necrotic teeth with open apex are difficult to manage. The situation becomes more complex if the tooth has a fracture line. This case report describes the management of a traumatised tooth that had already undergone unsuccessful endodontic treatment with a large periapical lesion and open apex along with a fracture line in the root. An attempt was made to save the tooth by using mineral trioxide aggregate (MTA) cement for orthograde filling, retrograde filling and also for sealing of the fracture line. Moreover, the bone defect was filled with autogenous bone harvested from the external oblique ridge. MTA, a bioactive tricalcium silicate cement, has been used in treating complex endodontic cases as it shows promising potential by inducing the biological mechanisms necessary for repair of involved teeth. A 1-year follow-up showed progressive healing as evident by radiographs and lack of any clinical signs and symptoms. ER -