RT Journal Article
SR Electronic
T1 Orbital metastasis from an occult breast carcinoma (T0, N1, M1)
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr-2017-223542
DO 10.1136/bcr-2017-223542
VO 2018
A1 Rita Pinto Proença
A1 Júlia Fernandes
A1 Miguel N Burnier
A1 Rui Proença
YR 2018
UL http://casereports.bmj.com/content/2018/bcr-2017-223542.abstract
AB The authors report a case of an orbital metastasis from an occult breast carcinoma. A 66-year-old woman presented with a growing left orbital tumour. Orbital CT scan was consistent with lymphoma. However, ocular pathology revealed small neoplastic cells showing an ‘indian file pattern’ suggestive of metastatic carcinoma and immunohistochemistry was positive for CK7, CK CAM5.2 and oestrogen receptor. A systemic evaluation was then performed with mammogram, breast ultrasound and MRI considered normal. An exhaustive systemic evaluation revealed multiple bone lesions, a right axillary lymph node lesion, which presented the same pattern on pathology and immunohistochemistry, with no evidence of a primary tumour. A diagnosis of a metastatic lobular carcinoma of the breast (T0, N1, M1) was made and the patient was started on chemotherapy and adjuvant hormonal therapy.