RT Journal Article
SR Electronic
T1 Rocuronium for control of muscle spasms in a tetanus patient with chronic methamphetamine use disorder
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr-2018-224391
DO 10.1136/bcr-2018-224391
VO 2018
A1 Clare Angeli Guinto Enriquez
A1 Joshua Emmanuel Edillon Abejero
A1 Philip A Ramiro
A1 Carissa Paz Dioquino Maligaso
YR 2018
UL http://casereports.bmj.com/content/2018/bcr-2018-224391.abstract
AB This is a case of a 31-year-old Filipino man with chronic methamphetamine use disorder who developed tetanus from a necrotic skin graft over his left calcaneus, which was fractured after a motor vehicular accident. During the course of his illness, the patient’s muscle spasms were unusually refractory to benzodiazepine, which is the first-line drug used in the management of muscle spasms. The muscle spasms were successfully controlled on the seventh day of illness with rocuronium at a dose of 10 μg/kg/min and midazolam at 0.30 mg/kg/hour. Both infusions were tapered off until the 23rd day of illness. The patient was discharged on the 30th day of illness, improved and stable.