RT Journal Article SR Electronic T1 Apixaban-induced subdural bleeding: case presentation and literature review JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr-2018-224495 DO 10.1136/bcr-2018-224495 VO 2018 A1 Eman Alayad A1 Sami Khairy A1 Ahmed Aloraidi YR 2018 UL http://casereports.bmj.com/content/2018/bcr-2018-224495.abstract AB Apixaban is a factor Xa inhibitor which is a non-vitamin K dependent oral anticoagulant known tocause the lowest rate of intracranial bleeding among the same kind of inibitors. In this paper, we report a rare case in a 60-year-old man with a history of hypertension and oligodendroglioma on apixaban for deep venous thrombosis who presented to our hospital with decreased level of consciousness and slurred speech with rapid deterioration. We highlight the risk of subdural bleeding requiring immediate neurosurgical intervention due to apixaban, with literature review.