TY - JOUR T1 - Apixaban-induced subdural bleeding: case presentation and literature review JF - BMJ Case Reports DO - 10.1136/bcr-2018-224495 VL - 2018 SP - bcr-2018-224495 AU - Eman Alayad AU - Sami Khairy AU - Ahmed Aloraidi Y1 - 2018/03/30 UR - http://casereports.bmj.com/content/2018/bcr-2018-224495.abstract N2 - Apixaban is a factor Xa inhibitor which is a non-vitamin K dependent oral anticoagulant known tocause the lowest rate of intracranial bleeding among the same kind of inibitors. In this paper, we report a rare case in a 60-year-old man with a history of hypertension and oligodendroglioma on apixaban for deep venous thrombosis who presented to our hospital with decreased level of consciousness and slurred speech with rapid deterioration. We highlight the risk of subdural bleeding requiring immediate neurosurgical intervention due to apixaban, with literature review. ER -