TY - JOUR T1 - Possible anti-VGKC autoimmune limbic encephalitis associated with SIADH JF - BMJ Case Reports DO - 10.1136/bcr-2017-223484 VL - 2018 SP - bcr-2017-223484 AU - Nicholas Black AU - Hazim Hamada Y1 - 2018/03/06 UR - http://casereports.bmj.com/content/2018/bcr-2017-223484.abstract N2 - An 80-year-old woman presented with a 5-week history of increasing confusion. Examination was remarkable only for deficits in short-term memory and paranoid thoughts. Blood tests revealed hyponatraemia, and further biochemical testing was consistent with syndrome of inappropriate antidiuretic hormone (SIADH). After an exhaustive diagnostic workup for causes of SIADH, the only abnormal finding was a mildly raised antivoltage-gated potassium channel (VGKC) titre of 185 pmol/L (0–69) consistent with possible anti-VGKC autoimmune limbic encephalitis. However, other diagnostic features were absent. She is currently undergoing outpatient investigation for other causes of memory loss. ER -