RT Journal Article
SR Electronic
T1 Two patients with localised hyperhidrosis of the hand based on functional and structural abnormalities of sweat glands
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr-2017-222530
DO 10.1136/bcr-2017-222530
VO 2018
A1 Bjørn H Kristiansen
A1 Kim H Lindahl
A1 Kristine A U Pallesen
A1 Anette Bygum
YR 2018
UL http://casereports.bmj.com/content/2018/bcr-2017-222530.abstract
AB A 14-year-old girl and a 30-year-old woman presented with localised hyperhidrosis on the dorsal hand and wrist, respectively, provoked by different stimuli such as physical activity and minor trauma to the skin. The skin was seemingly normal in both patients where an iodine–starch test revealed a well-demarcated area of hyperhidrosis. Following histopathological examination, the diagnosis was unilateral localised hyperhidrosis in both cases; one with normal histology and one with a nevus sudoriferous. Both patients were successfully treated with botulinum toxin type A. The 30-year-old woman additionally used low-dose propantheline bromide periodically and experienced long-term remission on this therapy. Hyperhidrosis may embarrass and interfere with patients’ school and careers, and it is therefore important to tailor an effective individual treatment.