RT Journal Article SR Electronic T1 Efficacy and safety of maintenance electroconvulsive therapy for sustaining resolution of severe aggression in a major neurocognitive disorder JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr-2017-222100 DO 10.1136/bcr-2017-222100 VO 2018 A1 Melanie Isabella Selvadurai A1 Robyn Waxman A1 Omar Ghaffar A1 Ilan Fischler YR 2018 UL http://casereports.bmj.com/content/2018/bcr-2017-222100.abstract AB We report a novel electroconvulsive therapy (ECT) regimen for sustaining the resolution of behavioural and psychological symptoms of dementia (BPSD) using alternating acute and maintenance ECT (M-ECT) trials. A 64-year-old man presenting with major neurocognitive disorder was admitted for acute behavioural disturbances and physical aggression. With few treatment options, the impact on patients’ quality of life often supersedes cognitive symptoms and is a predictor of long-term institutionalisation. Recent studies indicate that ECT may be an effective and safe way to address BPSD. Clinicians have little information about when and how to stop a successful course of acute ECT or the long-term advantages of M-ECT with subsequent intermittent acute ECT. This case emphasises the benefit of M-ECT and describes potential challenges associated with abrupt discontinuation. This case is the first to detail tapering ECT for treatment of aggression in dementia by interchanging acute and M-ECT courses in response to symptom burden.