RT Journal Article SR Electronic T1 Challenging and uncommon diagnosis of long-evolution ascites JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr-2017-222565 DO 10.1136/bcr-2017-222565 VO 2017 A1 Marta Gravito-Soares A1 Elisa Gravito-Soares A1 João Almeida A1 João Fraga A1 Luis Tomé YR 2017 UL http://casereports.bmj.com/content/2017/bcr-2017-222565.abstract AB This is a case report of a 45-year-old Caucasian man with chronic alcoholism. No history of liver disease or asbestos exposure. He complained of ascites during the last 3 years with worsening in the last year with severe ascites development. Diagnostic paracentesis showed SAAG 1.1 and high cellularity with neutrophil count >250 cells/µL. Ascitic fluid cytology revealed reactive mesothelial hyperplasia. Thoracoabdominopelvic ultrasonography/CT/MRI and fludeoxyglucose positron emission tomography/CT showed ‘omental cake’ pattern suggesting peritoneal carcinomatosis. An exploratory laparoscopy revealed moderate interloop adhesions and necrosis with whitish exudate in the right pelvic excavation. Biochemical/cytological/histological/microbiological study only revealed reactive mesothelial cells, necrosis and lymphohistiocytic inflammatory infiltrate. A second exploratory laparoscopy with liver and peritoneal biopsies and appendectomy/mesoappendix excision showed a well-differentiated tubulopapillary mesothelioma. The patient was referred for intraperitoneal chemotherapy and is undergoing monthly therapeutic paracentesis.