TY - JOUR T1 - Effect of autologous adipose-derived mesenchymal stem cell therapy in the treatment of a post-traumatic chondral defect of the knee JF - BMJ Case Reports DO - 10.1136/bcr-2017-220852 VL - 2017 SP - bcr-2017-220852 AU - Julien Freitag AU - Douglas Li AU - James Wickham AU - Kiran Shah AU - Abi Tenen Y1 - 2017/10/14 UR - http://casereports.bmj.com/content/2017/bcr-2017-220852.abstract N2 - Isolated chondral defects have a limited capacity to heal and predispose to the development of osteoarthritis. Current surgical management can be unpredictable in outcome. Improved understanding of the action of mesenchymal stem cells (MSCs) has seen renewed interest in their role in cartilage repair. A 26-year-old athlete presented with a post-traumatic, isolated patella chondral defect. The patient underwent an arthroscopy with removal of a chondral loose body. After failure to symptomatically improve 12 months following surgery, the patient received intra-articular autologous adipose-derived mesenchymal stem cell (ADMSC) therapy. ER -