PT  - JOURNAL ARTICLE
AU  - Julien Freitag
AU  - Douglas Li
AU  - James Wickham
AU  - Kiran Shah
AU  - Abi Tenen
TI  - Effect of autologous adipose-derived mesenchymal stem cell therapy in the treatment of a post-traumatic chondral defect of the knee
AID  - 10.1136/bcr-2017-220852
DP  - 2017 Oct 14
TA  - BMJ Case Reports
PG  - bcr-2017-220852
VI  - 2017
4099  - http://casereports.bmj.com/content/2017/bcr-2017-220852.short
4100  - http://casereports.bmj.com/content/2017/bcr-2017-220852.full
AB  - Isolated chondral defects have a limited capacity to heal and predispose to the development of osteoarthritis. Current surgical management can be unpredictable in outcome. Improved understanding of the action of mesenchymal stem cells (MSCs) has seen renewed interest in their role in cartilage repair. A 26-year-old athlete presented with a post-traumatic, isolated patella chondral defect. The patient underwent an arthroscopy with removal of a chondral loose body. After failure to symptomatically improve 12 months following surgery, the patient received intra-articular autologous adipose-derived mesenchymal stem cell (ADMSC) therapy.