RT Journal Article SR Electronic T1 Nocturnal reactive hypoglycaemia well treated subjectively and objectively with voglibose JF BMJ Case Reports FD BMJ Publishing Group Ltd SP bcr-2017-220295 DO 10.1136/bcr-2017-220295 VO 2017 A1 Hiroyuki Koyama A1 Hideomi Ohguchi A1 Takashi Yagi A1 Kenro Imaeda YR 2017 UL http://casereports.bmj.com/content/2017/bcr-2017-220295.abstract AB Clinicians sometimes encounter difficulty in diagnosing hypoglycaemia. Here, we present a case report of a 53-year-old woman with recurrent nocturnal hypoglycaemia. A continuous glucose monitoring system (CGMS) revealed postprandial hyperglycaemia and subsequent hypoglycaemia, and an oral glucose tolerance test showed an impaired glycaemic and delayed hyperinsulinaemic pattern. On the basis of these clinical findings, we diagnosed her unexplained hypoglycaemia as reactive hypoglycaemia. CGMS showed a sharp contrast of diurnal variation in blood glucose levels including hypoglycaemia between before and after treatment with an alpha-glucosidase inhibitor, voglibose. Her hypoglycaemic attacks disappeared.