TY - JOUR T1 - Nocturnal reactive hypoglycaemia well treated subjectively and objectively with voglibose JF - BMJ Case Reports DO - 10.1136/bcr-2017-220295 VL - 2017 SP - bcr-2017-220295 AU - Hiroyuki Koyama AU - Hideomi Ohguchi AU - Takashi Yagi AU - Kenro Imaeda Y1 - 2017/10/04 UR - http://casereports.bmj.com/content/2017/bcr-2017-220295.abstract N2 - Clinicians sometimes encounter difficulty in diagnosing hypoglycaemia. Here, we present a case report of a 53-year-old woman with recurrent nocturnal hypoglycaemia. A continuous glucose monitoring system (CGMS) revealed postprandial hyperglycaemia and subsequent hypoglycaemia, and an oral glucose tolerance test showed an impaired glycaemic and delayed hyperinsulinaemic pattern. On the basis of these clinical findings, we diagnosed her unexplained hypoglycaemia as reactive hypoglycaemia. CGMS showed a sharp contrast of diurnal variation in blood glucose levels including hypoglycaemia between before and after treatment with an alpha-glucosidase inhibitor, voglibose. Her hypoglycaemic attacks disappeared. ER -