TY - JOUR T1 - Obesity-related hypogonadism: a reversible condition JF - BMJ Case Reports DO - 10.1136/bcr-2017-220416 VL - 2017 SP - bcr-2017-220416 AU - Stamatios Zouras AU - Jeffrey W Stephens AU - David Price Y1 - 2017/06/23 UR - http://casereports.bmj.com/content/2017/bcr-2017-220416.abstract N2 - Obesity is associated with hypogonadism. While this association is widely accepted, the underlying mechanisms remain unclear. Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. We present the case of a morbidly obese man aged 30 years with hypogonadotrophic hypogonadism that underwent a Roux-en-Y gastric bypass operation. Following the surgical treatment of his obesity, the testosterone level returned to normal with improvements in hypogonadal symptoms, which allowed discontinuation of exogenous testosterone therapy. This case report demonstrates reversal of hypogonadism following weight loss with restoration of gonadal function. ER -