RT Journal Article
SR Electronic
T1 Obesity-related hypogonadism: a reversible condition
JF BMJ Case Reports
FD BMJ Publishing Group Ltd
SP bcr-2017-220416
DO 10.1136/bcr-2017-220416
VO 2017
A1 Stamatios Zouras
A1 Jeffrey W Stephens
A1 David Price
YR 2017
UL http://casereports.bmj.com/content/2017/bcr-2017-220416.abstract
AB Obesity is associated with hypogonadism. While this association is widely accepted, the underlying mechanisms remain unclear. Furthermore, obesity is a risk factor for hypogonadism and conversely hypogonadism may be a risk factor for obesity. We present the case of a morbidly obese man aged 30 years with hypogonadotrophic hypogonadism that underwent a Roux-en-Y gastric bypass operation. Following the surgical treatment of his obesity, the testosterone level returned to normal with improvements in hypogonadal symptoms, which allowed discontinuation of exogenous testosterone therapy. This case report demonstrates reversal of hypogonadism following weight loss with restoration of gonadal function.